Life Tips 25/06/2025 15:52

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Millennials were found to be hardest-hit in new anaylsis of data
Cancer is often associated with older age, but recent trends show that certain forms of the disease, particularly bowel cancer, are increasingly affecting younger populations. A new study, published in the Annals of Internal Medicine, reveals a surprising rise in appendiceal cancer—an uncommon form of the disease.
The study, which analyzed data from over 4,000 people in the US, found that compared to older generations, the incidence of appendiceal cancer—also known as appendix cancer—has tripled among Gen X and quadrupled among millennials.
“There is a disproportionate impact of appendix cancer on younger individuals,” said Andreana Holowatyj, the study’s lead author from Vanderbilt University Medical Center, speaking to NBC News.
The researchers suggest that environmental, lifestyle, and genetic factors, particularly those that emerged after World War II, may contribute to this alarming rise in appendix cancer. They highlight the role of dietary changes, shifts in gut bacteria, and the increasing prevalence of gastrointestinal conditions as potential factors driving this trend.
“Similar patterns have been observed in other gastrointestinal cancers, suggesting a shared underlying cause contributing to this growing cancer burden across generations,” the study explained.
While the study, released yesterday, did not include data from the UK, a similar 2022 study did. That research, published in BJS Open, also found a marked increase in the UK, with appendix cancer cases rising more than fourfold. The number of cases surged from 949 between 1995 and 2001 to 4,132 from 2010 to 2016.
However, appendix cancers remain exceedingly rare. According to the National Cancer Institute, they occur in just 1 to 2 people per million annually in the US. In the UK, with a smaller population, about 640 cases are diagnosed each year.
The appendix is a small pouch attached to the abdomen and is part of the intestines, which play a key role in nutrient absorption and waste elimination. While its exact function remains unclear, it is thought to be involved in supporting the immune system.
There are two primary types of appendiceal cancer: epithelial and neuroendocrine appendiceal cancer. Symptoms can vary but typically include abdominal pain, bloating, a palpable lump in the abdomen, nausea, and feeling full quickly after eating.

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